Antibiotic Susceptibility Profile of Uropathogenic Enterobacteria Isolated in the Bacteriology-Virology Laboratory of the CHNU of FANN During the Year 2022
Niokhor Ngobe SENE *
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Aïssatou Ahmet NIANG
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal and Bacteriology-Virology Department, FMPO, UCAD, Senegal.
Fatoumata Diallo
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
MBA Elhadji Bambo DIAKHABY
Gaston Berger University, Saint Louis, US.
Youssoupha FALL
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Antoine MBAYE GAYE
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Hamidou BA
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Ramata KANE
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Mame Ngoné KANOUTE
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal.
Habibou SARR
Assane SECK University, Ziguinchor, Senegal.
Assane DIENG
Bacteriology-Virology Department, FMPO, UCAD, Senegal.
Seynabou LO
Gaston Berger University, Saint Louis, US.
Mouhamadou Lamine DIA
Bacteriology-Virology Laboratory, Fann University Hospital, Senegal and Bacteriology-Virology Department, FMPO, UCAD, Senegal.
*Author to whom correspondence should be addressed.
Abstract
This was a retrospective study of urine cytobacteriological examinations (ECBU) aimed at determining the antibiotic sensitivity profile of enterobacteria isolated in urinary tract infections at the bacteriology and virology laboratory of the Fann National University Hospital during the period 2022. The antibiogram was carried out by the diffusion method in agar medium according to the recommendations of the Antibiogram Committee of the French Society of Microbiology CA-SFM 2022 and patient data were extracted from the laboratory register, entered into Excel and analyzed with SPSS IBM 25 software. The prevalence of UTIs was 23.7%, enterobacteria represented 70.32% of the isolated germs with a predominance of E. coli (48.5%) followed by K. pneumonia (23.7%) and Enterobacter spp. (11. 6%). It is noted poor susceptibility of the strains to beta-lactams, with extended spectrum Beta-Lactamase rates of 46% for E. coli, 53.5% for K. pneumoniae, and 50% for Enterobacter spp. ESBL-Es had good susceptibility to imipenem and amikacin (91.9% and 83.7%), respectively. However, poor activity was noted with floroquinolones, with resistance rates of 66.7% for ciprofloxacin and 62% for norfloxacin.
Keywords: Prevalence, antibiotic, resistance, uropathogens, susceptibility